THE KIDNEY STONE BOOK

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Lucas Cranach the Elder (1475 – 1553) painted the Judgement of Paris between 1512 and 1514. The painting hangs in the Metropolitan Museum of Art. Do Athena, Hera, and Aphrodite foresee Agamemnon dead, the burning towers, Hector at the gates of Ileum? Surely Paris, of his fateful judgment, knew nothing. And these violent, shape changing deities, why would they draw, thus, two civilizations into the fire?

KIDNEY STONES IN GENERAL 

INTRODUCTION TO STONE DISEASE 

WHAT STONES ARE

STONES AS OBJECTS – 

MATRIX OF STONES – D

TYPES OF STONES – A PRIMER 

STONE ANALYSIS

  1. HOW OFTEN – DO WE ANALYSE EVERY STONE?

  2. QUALITY OF STONE ANALYSIS – ARE LABS RELIABLE?

  3. NEPHROCALCINOSIS – WHAT THIS TERM MEANS; IS IT USEFUL?

WHAT STONES DO

PAIN – FROM OBSTRUCTION, FROM NON-OBSTRUCTING STONES

OBSTRUCTION

INFECTION

BLEEDING

KIDNEY DISEASE

HIGH BLOOD PRESSURE

WHAT CAUSES STONES

SUPERSATURATION – AN OVERVIEW 

  1. WHAT IS IT AND HOW IS IT MEASURED – CHARMING INTRODUCTION 

    1. SCIENCE OF SUPERSATURATION – D
    2. VIDEO SCIENCE AND MEASUREMENT OF SUPERSATURATION  
    3. USE OF SUPERSATURATION IN PRACTICE – D
    4. 24 HOUR URINE SUPERSATURATION MEASUREMENTS – D
  2. MAIN FACTORS THAT DETERMINE SUPERSATURATION

    1. URINE VOLUME – D
    2. CALCIUM
      1. HYPERCALCIURIA IN GENERAL 
      2. IDIOPATHIC HYPERCALCIURIA D
        1. ROLE OF SODIUM
        2. BONE DISEASE
    3. OXALATE
      1. LOW OXALATE DIET P
      2. OXALATE PHYSIOLOGY D
    4. CITRATE
      1. CALCIUM BINDING D
      2. CRYSTAL INHIBITION D
      3. CITRATE PHYSIOLOGY AND HOW POTASSIUM CITRATE WORKS D
    5. URINE pH
      1. CALCIUM PHOSPHATE STONES
      2. URIC ACID STONES

INHIBITOR FAILURE

  1. CITRATE – UPPER LIMIT OF METASTABILITY D

  2. LARGE MOLECULES D

SPECIAL ISSUES

  1. INFECTION STONES

  2. CYSTINE STONES

DIAGNOSTIC EVALUATION

ORGANIZING YOUR EVALUATION

  1. PUTTING IT ALL TOGETHER  

  2. FIVE STEPS TO STONE PREVENTION 

  3. HOW TO BE A SUCCESSFUL PATIENT 

24 HOUR URINE COLLECTIONS

  1. HOW TO DO 24 HOUR URINE COLLECTIONS

  2. HOW TO READ YOUR 24 HOUR URINE REPORT

    1. FIVE QUESTIONS TO ASK 
    2. CALCIUM STONE FORMERS –
    3. URIC ACID STONE FORMERS –

URETEROSCOPY – A DIAGNOSTIC AND THERAPEUTIC MODALITY

MY STYLE OF PRACTICE

TAKE CHARGE OF YOUR STONE PREVENTION

MANAGEMENT OF STONES

STONE PASSAGE

STONE BURDEN

MODALITIES

  1. SHOCK WAVE LITHOTRIPSY

  2. URETEROSCOPY

  3. PERCUTANEOUS NEPHROLITHOTOMY

CALCIUM STONES

HOW THEY FORM VIDEO

GROWTH ON PLAQUE

  1. ROLE OF IMMUNITY D

  2. ASSESSMENT OF PLAQUE BY CT SCAN D

GROWTH ON PLUGS D

MSK D

IDIOPATHIC – NO SYSTEMIC CAUSE

PHENOTYPES

  1. CALCIUM OXALATE STONE FORMERS

  2. CALCIUM PHOSPHATE STONE FORMERS

  3. MSK

TREATMENTS – ALL ARTICLES ARE RECOMMENDED FOR PATIENTS

  1. FLUIDS

    1. HOW TO DRINK ENOUGH FLUIDS
    2. VARIETY OF FLUIDS
    3. WHY DO SOME PEOPLE NOT DRINK ENOUGH WATER
    4. WEB APPS AND SMART BOTTLES – WORTHWHILE OR NOT; A PATIENT POLL
    5. Does Water Prevent Stones – What’s your bet?
  2. THE KIDNEY STONE DIET

    1. HOW TO EAT THE KIDNEY STONE DIET
    2. THE SCIENCE OF THE KIDNEY STONE DIET
    3. THE POLITICS AND SCIENCE OF THE US DIET GUIDELINES
    4. LOW SODIUM DIET
    5. HIGH CALCIUM LOW SODIUM DIET
    6. DIET PROTEIN INTAKE
    7. LOW OXALATE DIET
  3. DRUGS

    1. THIAZIDE – REVIEW OF TRIALS
    2. POTASSIUM CITRATE – OVERVIEW WITH LINKS – PAPERS OF CHARLES PAK
      1. STONE PREVENTION – REVIEW OF TRIALS
      2. COST OF POTASSIUM CITRATE
  4. INTEGRATION OF FLUIDS DIET AND MEDS: TREATMENT STRATEGY AND REVIEW OF TRIALS

  5. COMMENTARY – ARTICLES ABOUT THE QUALITY OF TREATMENTS

    1. ACP FLUID GUIDELINES
    2. AUA FLUID GUIDELINES
    3. ACP DRUG GUIDELINES
    4. EXPERT REBUKE OF ACP REVIEW
    5. AUA DRUG GUIDELINES
    6. FALSE CLAIMS
      1. COKE TREATMENT
  6. CASES OF IDIOPATHIC CALCIUM STONES

    1. A COMMON TYPE OF PATIENT
    2. UNEXPECTED EXTREME HYPEROXALURIA OF UNKNOWN CAUSE
    3. LOW SODIUM DIET TREATMENT SUCCESS BY MARRIAGE
    4. MSK DIAGNOSED AT PERCUTANEOUS NEPHROLITHOTOMY

SECONDARY TO SYSTEMIC DISEASES

PHPT

  1. DISEASE PATHOGENESIS
  2. HOW STONES FORM
  3. DIAGNOSTIC ISSUES
  4. TREATMENT AND OUTCOME
  5. RESIDUAL HYPERCALCIURIA

PH1

  1. PATHOGENESIS
  2. HOW STONES FORM
  3. KIDNEY DAMAGE AND DIALYSIS
  4. PALLIATION
  5. TRANSPLANTATION

RTA

  1. PATHOGENESIS
  2. DIAGNOSTIC ISSUES
  3. HETEROZYGOSITY
  4. HOW STONES FORM
  5. TREATMENT AND OUTCOME
  6. KIDNEY DAMAGE AND CKD

BOWEL DISEASES

  1. ENTERIC HOX
    1. IBD
    2. SHORT BOWEL
    3. BARIATRIC
  2. ILEOSTOMY

RARE HEREDITARY CAUSES

  1. DENT DISEASE
  2. BARTTER SYNDROME
  3. ADHH
  4. CYP 24 DEFECTS
  5. OTHERS

C. URIC ACID STONES

D. CYSTINE STONES

E. STRUVITE STONES

F. SCIENCE AND KIDNEY STONE DISEASE – 

  1. HOW SCIENCE AND MEDICINE RELATE TO EACH OTHER
  2. THREE SCIENCES IN MEDICINE
  3. BASIC SCIENCE IN MEDICAL PRACTICE
  4. APPLIED SCIENCE IN MEDICAL PRACTICE

 

3 Responses to “THE KIDNEY STONE BOOK”

  1. Laura Bousada

    Dear Doctor F. Coe. You are a dedicated genius. Thank you. This work is so special and out of the ordinary. You are an amazing man and doctor. I wish I could meet you. Your write with pizazz and laughter and seriousness and wisdom. What can we say but that you are a blessing.Thank you for your work. Thank you for your compassion. Thank you for caring. Thank you for making these pages a reality. My long doctor of 9 years asked me ” what does he get from this why does he do it” I said to help people’ He just was a bit stunned. I hope that your holidays was nice and your new year even better. Bless you

    Reply
    • Fredric Coe, MD

      Hi Laura, I am surprised your doctor was surprised. I get a lot from this. My warmest wishes for a healthy and wonderful year for you and your family, Fred

      Reply
  2. Jennifer Austin

    What a wonderful body of work this table represents. I am eternally grateful to Dr. Coe for his important research. It is so very valuable for so many of us. Thank you so much for all that you do!

    Reply

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