by Dr Fredric Coe | Oct 5, 2024 | For Scientists
This is the first of a group of posts about science. They are new in that I attempt to embed science in the larger context of society and commerce, and in the special case of medicine – the only case where I have real expertise. Examples are important to...
by Dr Fredric Coe and Dr James Williams PhD | May 9, 2024 | Book Topics, For Doctors, For Patients, For Scientists
The magnificent painting (oil on oak panel) by Hieronymus Bosch (“The Extraction of the Stone of Madness”), created between 1501-1505), dwells in the Museo del Prado since 1839, and has a provenance unbroken from its first owner, Philip of Burgundy, Bishop...
by Dr Fredric Coe | Nov 18, 2023 | For Doctors, For Patients, For Scientists
Plaque is a collection of calcium phosphate crystals in the tissues of the kidneys. Plugging is deposits of crystals that fill the interior of the kidney tubules. Both are visible to surgeons during kidney stone surgery procedures. Plaque is certainly part of common...
by Dr Fredric Coe | Apr 7, 2023 | For Doctors, For Patients, For Scientists
I picture a younger me on this article because the long line of thiazide trials stretches back decades in time to when I looked just like the photograph. The large picture that heads this article depicts my spreadsheet of all of the trials I have reviewed, and this...
by Dr Fredric Coe | Jan 13, 2023 | For Doctors, For Patients, For Scientists
Long ago, physicians gave calcium kidney stone formers oral phosphate supplements to reduce urine calcium and kidney stone production. But trials were small and informal, so when a single and excellent trial showed lack of benefit our generation left phosphate by the...