by Dr Fredric Coe | Apr 7, 2023 | For Doctors, For Patients, For Scientists
I picture a younger me on this article because the long line of thiazide trials stretches back decades in time to when I looked just like the photograph. The large picture that heads this article depicts my spreadsheet of all of the trials I have reviewed, and this...
by Dr Fredric Coe | Jan 13, 2023 | For Doctors, For Patients, For Scientists
Long age, physicians gave calcium kidney stone formers oral phosphate supplements to reduce urine calcium and kidney stone production. But trials were small and informal, so when a single and excellent trial showed lack of benefit our generation left phosphate by the...
by Dr Fredric Coe | Dec 26, 2020 | For Doctors, For Patients, For Scientists
The title is my story’s conclusion. We know that calcium phosphate crystals in plaque, plugs, and the vast majority of stones are hydroxyapatite, yet when we measure supersaturation with respect to calcium phosphate we measure that for brushite, the pretty...
by Dr Fredric Coe | Nov 21, 2020 | Site Logic
This entire site concerns the science from which we have derived what we offer to patients for prevention of kidney stones. Every article rests on a base of established and peer reviewed science. We Have Always Had a Science Page For years I have posted articles about...
by Dr Fredric Coe | Mar 16, 2020 | For Doctors, For Patients, For Scientists
Pieter Bruegel the Elder (1530-1569) painted ‘Children’s Games’ in 1560. It resides in the Kunsthistorisches Museum, Vienna. On the Rise If you read the many reviews that abound (Pediatr Ann. 2017;46(6):e242-e244; Bowen D K Urol Clin N Am 45...